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Section 4.4
Testing for Antibodies
A patient is suspected of having paroxysmal cold hemoglobinuria (PCH). Which pattern of reactivity is characteristic of the Donath–Landsteiner antibody, which causes this condition?
The antibody attaches to RBCs at 4°C and causes hemolysis at 37°C
The antibody attaches to RBCs at 37°C and causes agglutination at the IAT phase
The antibody attaches to RBCs at 22°C and causes hemolysis at 37°C
The antibody attaches to RBCs and causes agglutination at the IAT phase
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